Special Interest Group 2021: Epilepsy (recording)
*This activity does not award CME*
*This activity is free of charge to those registered for ANA2021. Please click continue to access the content. Please contact us if you are prompted to pay the fee and were registered for the meeting.*
Session Title: Epilepsy Genetics: Bringing Basic Science to the Clinic
Description: Speakers will discuss the epilepsy genetics from preclinical research to clinical applications. Preclinical research focused on the development of antisense oligonucleotide therapy, precision medicine in rare genetic disorders, somatic variants in the brain and non-monogenetic epilepsy will be discussed. Finally, we will discuss the utilization of genetics in clinical practice.
Chair: Kathryn Davis, MD, MS, FAES, University of Pennsylvania
Co-Chair: Chloe Hill, MD, MS, University of Michigan
Objective(s):
- Utilize genetics data in epilepsy patients
- Understand ongoing ASO genetic trials
- Understand how to diagnose and treat patients with underlying genetic causes of their epilepsy
Presentations:
Dancing to a Different Tune: TANGO Gives Hope for Dravet Syndrome
Speaker:
Lori Isom, PhD
University of Michigan, Medical School
Pv+ Interneurons Are Non-Cell Autonomously Dysregulated in Depdc5-Associated Epilepsies
Oral Presenter:
Tao Yang, PhD
University of Michigan, Department of Neurology
Precision Diagnosis in Epilepsy--a First Step Toward Precision Medicine
Speaker:
Ann Poduri, MD, MPH
Boston Children's Hospital, Harvard Medical School
Non-cell Autonomous Hyperexcitability Underlies Focal Epileptogenesis Mediated by Low-level Brain Somatic Mutations in Mtor
Oral Presenter:
Hyunyong Koh, MD, PhD
Boston Children's Hospital
Genetics in the Clinic: Beyond Monogenic Epilepsies
Speaker:
Colin Ellis, MD
University of Pennsylvania
Target Audience
ANA2021 Attendees
Please visit https://2021.myana.org/sig-series for details.