Special Interest Group 2021: ANA-AHS Headache (recording)
*This activity is free of charge to those registered for ANA2021. Please click continue to access the content. Please contact us if you are prompted to pay the fee and were registered for the meeting.*
Session Title: Emerging Concepts in Migraine Pathophysiology
Description: Headache is the second to third leading cause of global years lived with disability. Migraine headaches represent one of the most disabling headache diagnoses, affecting 12% of the general population. The economic and social impact of migraine, particularly in women, highlight the need to better understand mechanisms involved in migraine headache generation and its accompanying symptoms. Basic science and clinical research in migraine have culminated in new translational targets, providing renewed hope for migraine patients. Despite these recent advances, there are still many unanswered questions about disease mechanism. The focus of this session is to highlight emerging discoveries in migraine research that increase our understanding of the biological mechanisms of trigeminal pain, cortical events involved in migraine aura and accompanying incapacitating symptoms like light sensitivity.
Chair: William Renthal, MD, PhD, Brigham and Women’s Hospital, Harvard Medical School
Co-Chair: Andrea Harriott, MD, PhD, Massachusetts General Hospital
Objective(s):
At the end of this activity, participants will be able to:
- Discuss pathophysiological mechanisms of migraine
- Identify emerging concepts from preclinical migraine models
- Describe mechanisms involved in accompanying features of migraine including photophobia
Presentations:
Non-Canonical Glutamate Signaling and Migraine: Emerging Concepts in Cortical Hyperexcitability
Speaker:
KC Brennan, MD
University of Utah
The Role of Neuronal Complexity and HDAC6 in Models of Chronic Migraine
Speaker:
Amynah Pradhan, PhD (This presentation has been omitted from the recording. The speaker did not consent to sharing of the recording.)
University of Illinois at Chicago
The Role of Intrinsically Photosensitive Retinal Ganglion Cells in Photophobia
Speaker:
Eric Kaiser, MD, PhD
University of Pennsylvania
A Midbrain Circuit That Mediates Headache Aversiveness in Rats
Speaker:
Maggie Wuang, MD, PhD (This presentation has been omitted from the recording. The speaker did not consent to sharing of the recording.)
University of California, San Francisco
Efferent Projections of Cgrp/Calca-expressing Parabrachial Neurons in Mice
Oral Presenter:
Dake Huang, BS
University of Iowa
Target Audience
ANA2021 Attendees
Please visit https://2021.myana.org/sig-series for details.
Available Credit
- 1.00 AMA PRA Category 1 Credit™The American Neurological Association is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The American Neurological Association designates this Enduring material for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
- 1.00 Participation