Description: Autoimmune neurology encompasses the diagnosis and treatment of neurological disorders with an autoimmune basis. These disorders can affect diverse areas of the immune system and produced severe but treatable disorders. This SIG will cover novel research into underlying disease mechanisms, diagnosis and treatments. 

Chair: Anusha Yeshokumar, MD, Icahn School of Medicine at Mount Sinai

Co-Chair: Claude Steriade, MD, MSCI, New York University, Langone Health

Objective(s):

• Describe candidate biomarkers of neurodegeneration in patients with autoimmune encephalitis
• Recognize the complementary role of inflammatory biomarkers in the diagnosis and follow-up of patients with autoimmune encephalitis
• Describe the approach currently used in the design of animal models for autoimmune encephalitis and how they may be used in the examination of clinically-relevant questions

Presentations:

CSF Biomarkers in Autoimmune Encephalitis

Speaker:

Gregory Day, MD, MSc, MSCI

Mayo Clinic

Clinical Outcomes Following Status Epilepticus in Anti-nmdar Encephalitis

Oral Presenter:

Seon-Jae Ahn, MD

Seoul National University Hospital

Genomic and Transcriptomic-wide Analysis Identifies Novel Genetic Risk Loci and Prioritization of Therapies for Myasthenia Gravis

Oral Presenter:

Ruth Chia, PhD

National Institutes on Aging, National Institutes of Health

High Frequency of Asymptomatic Optic Nerve Enhancement in Aquaporin-4-Positive Neuromyelitis Optica Spectrum Disorder

Oral Presenter:

Shailee Shah, MD

Mayo Clinic

Animal Models of Autoimmune Encephalitis

Speaker:

Jenny Linnoila, MD, PhD

Massachusetts General Hospital, Harvard Medical School