Special Interest Group 2021: ANA-AHS Headache

November 1, 2021

Session Title: Emerging Concepts in Migraine Pathophysiology

Description: Headache is the second to third leading cause of global years lived with disability. Migraine headaches represent one of the most disabling headache diagnoses, affecting 12% of the general population. The economic and social impact of migraine, particularly in women, highlight the need to better understand mechanisms involved in migraine headache generation and its accompanying symptoms. Basic science and clinical research in migraine have culminated in new translational targets, providing renewed hope for migraine patients. Despite these recent advances, there are still many unanswered questions about disease mechanism. The focus of this session is to highlight emerging discoveries in migraine research that increase our understanding of the biological mechanisms of trigeminal pain, cortical events involved in migraine aura and accompanying incapacitating symptoms like light sensitivity.

Chair: William Renthal, MD, PhD, Brigham and Women’s Hospital, Harvard Medical School

Co-Chair: Andrea Harriott, MD, PhD, Massachusetts General Hospital

Objective(s):
At the end of this activity, participants will be able to:

  • Discuss pathophysiological mechanisms of migraine
  • Identify emerging concepts from preclinical migraine models
  • Describe mechanisms involved in accompanying features of migraine including photophobia

Presentations:

Non-Canonical Glutamate Signaling and Migraine: Emerging Concepts in Cortical Hyperexcitability

Speaker:

KC Brennan, MD

University of Utah

The Role of Neuronal Complexity and HDAC6 in Models of Chronic Migraine

Speaker:

Amynah Pradhan, PhD

University of Illinois at Chicago

The Role of Intrinsically Photosensitive Retinal Ganglion Cells in Photophobia

Speaker:

Eric Kaiser, MD, PhD

University of Pennsylvania

A Midbrain Circuit That Mediates Headache Aversiveness in Rats

Speaker:

Maggie Wuang, MD, PhD

University of California, San Francisco

Efferent Projections of Cgrp/Calca-expressing Parabrachial Neurons in Mice

Oral Presenter:

Dake Huang, BS

University of Iowa

Target Audience

ANA2021 Attendees

Activity summary
Available credit: 
  • 1.50 AMA PRA Category 1 Credit™
    The American Neurological Association is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The American Neurological Association designates this Live activity for a maximum of 1.50 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
  • 1.50 Participation
Activity opens: 
10/21/2021
Activity expires: 
12/31/2021
Event starts: 
11/01/2021 - 11:30am EDT
Event ends: 
11/01/2021 - 1:00pm EDT
Add to calendar: 
Rating: 
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Please visit https://2021.myana.org/sig-series for details.

Disclosure link: 
Financial Disclosures

Available Credit

  • 1.50 AMA PRA Category 1 Credit™
    The American Neurological Association is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The American Neurological Association designates this Live activity for a maximum of 1.50 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
  • 1.50 Participation
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